Display All CHCHE Courses for 2019-20

Filtered CHCHE Courses (2019-20)

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General Chemistry

Ch 1 a 6 units (3-0-3) first term; Ch 1 b 9 units (4-0-5) second term  | 
Lectures and recitations dealing with the principles of chemistry. First term: Chemical bonding-electronic structure of atoms, periodic properties, ionic substances, covalent bonding, Lewis representations of molecules and ions, shapes of molecules, Lewis acids and bases, Bronsted acids and bases, hybridization and resonance, bonding in solids. Second term: Chemical dynamics-spectroscopy, thermodynamics, kinetics, chemical equilibria, electrochemistry, and introduction to organic chemistry. Graded pass/fail.
Instructors: Lewis (a), Robb, Miller (b)

Fundamental Techniques of Experimental Chemistry

6 units (1-3-2)  |  first, second, third terms
Introduces the basic principles and techniques of synthesis and analysis and develops the laboratory skills and precision that are fundamental to experimental chemistry. Freshmen who have gained advanced placement into Ch 41 or Ch 21, or who are enrolled in Ch 10, are encouraged to take Ch 3 a in the fall term. Freshmen who enter in academic years 2017, 2018, and 2019 must take Ch 3 a in their first nine terms of residence in order to be graded pass/fail. Freshmen entering in academic year 2020 and thereafter must take Ch 3 a in their first six terms of residence in order to be graded pass/fail.
Instructor: Mendez

Experimental Methods in Solar Energy Conversion

6 units (1-3-2)  |  first, second, third terms
Introduces concepts and laboratory methods in chemistry and materials science centered on the theme of solar energy conversion and storage. Students will perform experiments involving optical spectroscopy, electrochemistry, laser spectroscopy, photochemistry, and photoelectrochemistry, culminating in the construction and testing of dyesensitized solar cells. Freshmen who enter in academic years 2017, 2018, and 2019 must take Ch 3x in their first nine terms of residence in order to be graded pass/fail. Freshmen entering in academic year 2020 and thereafter must take Ch 3x in their first six terms of residence in order to be graded pass/fail.
Instructor: Mendez

Synthesis and Analysis of Organic and Inorganic Compounds

9 units (1-6-2)  | 
Introduction to methods of synthesis, separation, purification, and characterization used routinely in chemical research laboratories. Ch 4 a focuses on the synthesis and analysis of organic molecules; Ch 4 b focuses on the synthesis and analysis of inorganic and organometallic molecules. Ch 4 a, second term; Ch 4 b, third term.
Instructor: Mendez

Advanced Techniques of Synthesis and Analysis

Ch 5 a 12 units (1-9-2), second term; Ch 5 b 12 units (1-9-2), first term  | 
Modern synthetic chemistry. Specific experiments may change from year to year. Experiments illustrating the multistep syntheses of natural products (Ch 5 a), coordination complexes, and organometallic complexes (Ch 5 b) will be included. Methodology will include advanced techniques of synthesis and instrumental characterization. Terms may be taken independently. Part b not offered 2019-20.
Instructors: Grubbs (a), Agapie (b)

Physical and Biophysical Chemistry Laboratory

9 units (1-5-3)  |  second, third terms
Introduction to modern physical methods in chemistry and biology. Techniques include laser spectroscopy, microwave spectroscopy, electron spin resonance, nuclear magnetic resonance, mass spectrometry, FT-IR, fluorescence, scanning probe microscopies, and UHV surface methods. The two terms can be taken in any order. Part b not offered 2019-20.
Instructor: Okumura

Advanced Experimental Methods in Bioorganic Chemistry

9 units (1-6-2)  |  third term
Preference will be given to students who have taken Ch 5 a or Bi 10. This advanced laboratory course will provide experience in powerful contemporary methods used in chemical biology, including polypeptide synthesis and the selective labeling and imaging of glycoproteins in cells. Experiments will address amino acid protecting group strategies, biopolymer assembly and isolation, and product characterization. A strong emphasis will be placed on understanding the chemical basis underlying the successful utilization of these procedures. In addition, experiments to demonstrate the application of commercially available enzymes for useful synthetic organic transformations will be illustrated.
Instructor: Hsieh-Wilson

Experimental Procedures of Synthetic Chemistry for Premedical Students

9 units (1-6-2)  |  first term
Open to non-pre-medical students, as space allows. Introduction to methods of extraction, synthesis, separation and purification, and spectroscopic characterization of Aspirin, Tylenol, and medical test strips.
Instructor: Mendez

Chemical Synthesis and Characterization for Chemical Engineering

9 units (1-6-2)  |  third term
Instruction in synthesis, separation, purification, and physical and spectroscopic characterization procedures of model organic and organometallic compounds. Specific emphasis will be focused on following the scientific method in the study of model organic and inorganic materials. Enrollment priority given to chemical engineering majors.
Instructor: Mendez

Frontiers in Chemistry

1 unit (1-0-0) first, second terms; 6 units (1-4-1) third term  | 
Ch 10 ab is a weekly seminar by a member of the chemistry department on a topic of current research; the topic will be presented at an informal, introductory level. Ch 10 c is a research-oriented laboratory course, which will be supervised by a chemistry faculty member. Weekly class meetings will provide a forum for participants to discuss their research projects. Graded pass/fail.
Instructors: Dervan, Hoelz

Chemical Equilibrium and Analysis

9 units (3-0-6)  |  second term
This course will cover acid-base equilibria, complex ion formation, chelation, oxidation-reduction reactions, and partitioning equilibria. These topics will serve as the basis for introducing separation techniques such as gas and liquid chromatography and the hyphenated techniques associated with them (GC-MS, LC-MS, etc.) Laboratory activities will be integrated with the course topics.
Instructor: Rees

Chemical Equilibrium and Analysis Laboratory

10 units (0-6-4)  |  third term
Laboratory experiments are used to illustrate modern instrumental techniques that are currently employed in industrial and academic research. Emphasis is on determinations of chemical composition, measurement of equilibrium constants, evaluation of rates of chemical reactions, and trace-metal analysis.
Instructor: Dalleska

Physical Chemistry

9 units (3-0-6)  |  first, second, third terms
Atomic and molecular quantum mechanics, spectroscopy, chemical dynamics, statistical mechanics, and thermodynamics.
Instructors: Chan (a), Wei (b), Beauchamp (c)

Introduction to Biophysical Chemistry: Thermodynamics

9 units (3-0-6)  |  third term
Develops the basic principles of solution thermodynamics, transport processes, and reaction kinetics, with emphasis on biochemical and biophysical applications. Not offered 2019-20

Organic Chemistry

9 units (4-0-5)  |  first, second, third terms
The synthesis, structure, and mechanisms of reactions of organic compounds.
Instructors: Grubbs (a), Hsieh-Wilson (b), Reisman (c)

Chemical Research

Units in accordance with work accomplished.  | 
Offered to B. S. candidates in chemistry. Units in accordance with work accomplished. Prerequisite: consent of research supervisor. Experimental and theoretical research requiring a report containing an appropriate description of the research work.

Independent Reading in Chemistry

Units by arrangement  | 
Occasional advanced work involving reading assignments and a report on special topics. No more than 12 units in Ch 81 may be used as electives in the chemistry option.

Senior Thesis Research

9 units  |  first, second, third terms
Three terms of Ch 82 are to be completed during the junior and/or senior year of study. At the end of the third term, students enrolled in Ch 82 will present a thesis of approximately 20 pages (excluding figures and references) to the mentor and the Chemistry Curriculum and Undergraduate Studies Committee. The thesis must be approved by both the research mentor and the CUSC. An oral thesis defense will be arranged by the CUSC in the third term for all enrollees. The first two terms of Ch 82 will be taken on a pass/fail basis, and the third term will carry a letter grade.
Instructors: Okumura, staff

Oral Presentation

3 units (2-0-1)  |  second term
Training in the techniques of oral presentation of chemical and biochemical topics. Practice in the effective organization and delivery of technical reports before groups. Strong oral presentation is an essential skill for successful job interviews and career advancement. Graded pass/fail. Class size limited to 12 students.
Instructor: Bikle

Scientific Writing

3 units (2-0-1)  |  first, second, third terms
Training in the writing of scientific research papers for chemists and chemical engineers. Fulfills the Institute scientific writing requirement.
Instructors: Parker, Weitekamp

Chemistry Tutorials

3 units (1-0-2)  |  third term
Small group study and discussion on special areas of chemistry, chemical engineering, molecular biology, or biophysics. Instructors drawn from advanced graduate students and postdoctoral staff will lead weekly tutorial sessions and assign short homework assignments, readings, or discussions. Tutorials to be arranged with instructors before registration.
Instructor: Staff

Introduction to Inorganic Chemistry

9 units (4-0-5)  |  third term
Structure and bonding of inorganic species with special emphasis on spectroscopy, ligand substitution processes, oxidation-reduction reactions, organometallic, biological inorganic chemistry, and solid-state chemistry.
Instructors: Hadt, See

Intermediate Organic Chemistry

9 units (4-0-5)  |  second term
A survey of selected topics beyond introductory organic chemistry, including reaction mechanisms and catalysis.
Instructor: Fu

Introduction to Biochemistry

12 units (4-0-8)  |  first term
Lectures and recitation introducing the molecular basis of life processes, with emphasis on the structure and function of proteins. Topics will include the derivation of protein structure from the information inherent in a genome, biological catalysis, and the intermediary metabolism that provides energy to an organism.
Instructor: Clemons

Biochemistry of Gene Expression

12 units (4-0-8)  |  second term
Lectures and recitation on the molecular basis of biological structure and function. Emphasizes the storage, transmission, and expression of genetic information in cells. Specific topics include DNA replication, recombination, repair and mutagenesis, transcription, RNA processing, and protein synthesis.
Instructors: Campbell, Parker

Inorganic Chemistry

9 units (3-0-6)  |  first term
Introduction to group theory, ligand field theory, and bonding in coordination complexes and organotransition metal compounds. Systematics of bonding, reactivity, and spectroscopy of commonly encountered classes of transition metal compounds.
Instructors: Agapie, Hadt

Introduction to Electrochemistry

9 units (3-0-6)  |  first term
Discussion of the fundamentals and applications of electrochemistry with an emphasis on the structure of electrode-electrolyte interfaces, the mechanism by which charge is transferred across it, experimental techniques used to study electrode reactions, and application of electrochemical techniques to study materials chemistry. Topics may vary but usually include diffusion, cyclic voltammetry, coulometry, irreversible electrode reactions, the electrical double layer, and kinetics of electrode processes.
Instructor: See

Nature of the Chemical Bond

Ch 120 a: 9 units (3-0-6), third term; Ch 120 b: (1-1-7), first term  | 
Modern ideas of chemical bonding, with an emphasis on qualitative concepts useful for predictions of structures, energetics, excited states, and properties. Part a: The quantum mechanical basis for understanding bonding, structures, energetics, and properties of materials (polymers, ceramics, metals alloys, semiconductors, and surfaces), including transition metal and organometallic systems with a focus on chemical reactivity. The emphasis is on explaining chemical, mechanical, electrical, and thermal properties of materials in terms of atomistic concepts. Part b: The student does an individual research project using modern quantum chemistry computer programs to calculate wavefunctions, structures, and properties of real molecules.
Instructor: Goddard

Atomic-Level Simulations of Materials and Molecules

Ch 121 a: 9 units (3-0-6) second term; Ch 121 b (1-1-7) third term  | 
Application of Atomistic-based methods [Quantum Mechanics (QM) and Molecular Dynamics (MD)] for predicting the structures and properties of molecules and solids and simulating the dynamical properties. This course emphasizes hands-on use of modern commercial software (such as Jaguar for QM, VASP for periodic QM, and LAMMPS for MD) for practical applications and is aimed at experimentalists and theorists interested in understanding structures, properties, and dynamics in such areas as biological systems (proteins, DNA, carbohydrates, lipids); polymers (crystals, amorphous systems, co-polymers); semiconductors (group IV, III-V, surfaces, defects); inorganic systems (ceramics, zeolites, superconductors, and metals); organo-metallics, and catalysis (heterogeneous, homogeneous, and electrocatalysis). Ch121a covers the basic methods with hands-on applications to systems of interest using modern software. The homework for the first 5 weeks emphasizes computer based solutions. For the second 5 weeks of the homework each student proposes a short research project and uses atomistic simulations to solve it. Ch121b each student selects a more extensive research project and uses atomistic simulations to solve it.
Instructor: Goddard

Structure Determination by X-ray Crystallography

9 units (3-0-6)  |  first term
This course provides an introduction to small molecule X-ray crystallography. Topics include symmetry, space groups, diffraction by crystals, the direct and reciprocal lattice, Patterson and direct methods for phase determination, and structure refinement. It will cover both theoretical and applied concepts and include hands-on experience in data collection, structure solution and structure refinement.
Instructor: Takase

The Elements of Quantum Chemistry

9 units (3-0-6)  |  first, second, third terms
A treatment of quantum mechanics with application to molecular and material systems. The basic elements of quantum mechanics, the electronic structure of atoms and molecules, the interactions of radiation fields and matter, and time dependent techniques relevant to spectroscopy will be covered. The course sequence prepares students for Ch 225 and 226. Part (c) not offered 2019-20.
Instructors: Cushing (a), Weitekamp (b)

Molecular Spectra and Molecular Structure

9 units (3-0-6)  |  third term
Quantum mechanical foundations of the spectroscopy of molecules. Topics include quantum theory of angular momentum, rovibrational Hamiltonian for polyatomic molecules, molecular symmetry and permutation-inversion groups, electronic spectroscopy, density matricies, linear and nonlinear interactions of radiation and matter. Not offered 2019-20.
Instructor: Blake

Nuclear Chemistry

9 units (3-0-6)  |  first term
A survey course in the properties of nuclei, and in atomic phenomena associated with nuclear-particle detection. Topics include rates of production and decay of radioactive nuclei; interaction of radiation with matter; nuclear masses, shapes, spins, and moments; modes of radioactive decay; nuclear fission and energy generation. Given in alternate years; offered 2019-20.
Instructor: Burnett

Cosmochemistry

9 units (3-0-6)  |  first term
Examination of the chemistry of the interstellar medium, of protostellar nebulae, and of primitive solar-system objects with a view toward establishing the relationship of the chemical evolution of atoms in the interstellar radiation field to complex molecules and aggregates in the early solar system that may contribute to habitability. Emphasis will be placed on identifying the physical conditions in various objects, timescales for physical and chemical change, chemical processes leading to change, observational constraints, and various models that attempt to describe the chemical state and history of cosmological objects in general and the early solar system in particular. Given in alternate years; offered 2019-20.
Instructor: Blake

Introduction to Biophotonics

9 units (3-0-6)  |  first term
This course will cover basic optics and introduce modern optical spectroscopy principles and microscopy techniques. Topics include molecular spectroscopy; linear and nonlinear florescence microscopy; Raman spectroscopy; coherent microscopy; single-molecule spectroscopy; and super-resolution imaging. Not offered 2019-20.
Instructor: Wei

Chemical Dynamics

9 units (3-0-6)  |  third term
Introduction to the kinetics and dynamics of chemical reactions. Topics include scattering cross sections, rate constants, intermolecular potentials, classical two-body elastic scattering, reactive scattering, nonadiabatic processes, statistical theories of unimolecular reactions, photochemistry, laser and molecular beam methods, theory of electron transfer, solvent effects, condensed phase dynamics, surface reactions, isotope effects. Not offered 2019-20.
Instructor: Okumura

Principles and Applications of Semiconductor Photoelectrochemistry

9 units (3-0-6)  |  second term
The properties and photoelectrochemistry of semiconductors and semiconductor/liquid junction solar cells will be discussed. Topics include optical and electronic properties of semiconductors; electronic properties of semiconductor junctions with metals, liquids, and other semiconductors, in the dark and under illumination, with emphasis on semiconductor/liquid junctions in aqueous and nonaqueous media. Problems currently facing semiconductor/liquid junctions and practical applications of these systems will be highlighted. Part a Not offered 2019-20
Instructor: Lewis (b)

NMR Spectroscopy for Structural Identification

9 units (3-0-6)  |  third term
This course will address both one-dimensional and two-dimensional techniques in NMR spectroscopy which are essential to elucidating structures of organic and organometallic samples. Dynamic NMR phenomena, multinuclear, paramagnetic and NOE effects will also be covered. An extensive survey of multipulse NMR methods will also contribute to a clear understanding of two-dimensional experiments. (Examples for Varian NMR instrumentation will be included.) Not offered 2019-20.

Advanced Organic Chemistry

9 units (3-0-6)  |  first term
An advanced survey of selected topics in modern organic chemistry. Topics vary from year to year and may include structural and theoretical organic chemistry; materials chemistry; macromolecular chemistry; mechanochemistry; molecular recognition/supramolecular chemistry; reaction mechanisms; reactive intermediates; pericyclic reactions; and photochemistry. Not offered 2019-20.

Chemical Biology of Proteins

9 units (3-0-6)  |  first term
An advanced survey of current and classic topics in chemical biology. Content draws largely from current literature and varies from year-to-year. Topics may include the structure, function, and synthesis of peptides and proteins; enzyme catalysis and inhibition; cellular metabolism; chemical genetics; proteomics; posttranslational modifications; chemical tools to study cellular dynamics; and enzyme evolution.
Instructor: Ondrus

Bioorganic Chemistry of Nucleic Acids

9 units (3-0-6)  | 
The course will examine the bioorganic chemistry of nucleic acids, including DNA and RNA structures, molecular recognition, and mechanistic analyses of covalent modification of nucleic acids. Topics include synthetic methods for the construction of DNA and RNA; separation techniques; recognition of duplex DNA by peptide analogs, proteins, and oligonucleotide-directed triple helical formation; RNA structure and RNA as catalysts (ribozymes). Not offered 2019-20.

Polymer Chemistry

9 units (3-0-6)  |  first term
An introduction to the chemistry of polymers, including synthetic methods, mechanisms and kinetics of macromolecule formation, and characterization techniques.
Instructor: Robb

Polymer Physics

9 units (3-0-6)  |  third term
An introduction to the physics that govern the structure and dynamics of polymeric liquids, and to the physical basis of characterization methods used in polymer science. The course emphasizes the scaling aspects of the various physical properties. Topics include conformation of a single polymer, a chain under different solvent conditions; dilute and semi-dilute solutions; thermodynamics of polymer blends and block copolymers; polyelectrolytes; rubber elasticity; polymer gels; linear viscoelasticity of polymer solutions and melts. Not offered 2019-20.
Instructor: Wang

Tutorial in Organic Chemistry

6 units (2-0-4)  |  first term
Discussion of key principles in organic chemistry, with an emphasis on reaction mechanisms and problem-solving. This course is intended primarily for first-year graduate students with a strong foundation in organic chemistry. Meets during the first three weeks of the term. Graded pass/fail.
Instructors: Fu, Stoltz, Ondrus

Advanced Inorganic Chemistry

9 units (3-0-6)   |  second (Ch 153 a), third (Ch 153 c offered in 2019-20, alternating with Ch 153 b in subsequent years) terms
Ch 153 a: Topics in modern inorganic chemistry. Electronic structure, spectroscopy, and photochemistry with emphasis on examples from the modern research literature. Ch 153 b: Applications of physical methods to the characterization of inorganic and bioinorganic species, with an emphasis on the practical application of Moessbauer, EPR, and pulse EPR spectroscopies. Ch 153 c: Theoretical and spectroscopic approaches to understanding the electronic structure of transition metal ions. Topics in the 153bc alternate sequence may include saturation magnetization and zero-field splitting in magnetic circular dichroism and molecular magnetism, hyperfine interactions in electron paramagnetic resonance spectroscopy, Moessbauer and magnetic Moessbauer spectroscopy, vibronic interactions in electronic absorption and resonance Raman spectroscopy, and bonding analyses using x-ray absorption and/or emission spectroscopies.
Instructors: Gray, Winkler (a), Hadt/Peters (c)

Organometallic Chemistry

9 units (3-0-6)  |  second, third terms
A general discussion of the reaction mechanisms and the synthetic and catalytic uses of transition metal organometallic compounds. Second term: a survey of the elementary reactions and methods for investigating reaction mechanisms. Third term: contemporary topics in inorganic and organometallic synthesis, structure and bonding, and applications in catalysis. Part b not offered 2019-20.
Instructors: Peters, Agapie (a)

Chemistry of Catalysis

9 units (3-0-6)  |  third term
Discussion of homogeneous and heterogeneous catalytic reactions, with emphasis on the relationships between the two areas and their role in energy problems. Topics include catalysis by metals, metal oxides, zeolites, and soluble metal complexes; utilization of hydrocarbon resources; and catalytic applications in alternative energy approaches. Not offered 2019-20.

Introduction to Statistical Thermodynamics

9 units (3-0-6)  |  second term
An introduction to the fundamentals and simple applications of statistical thermodynamics. Foundation of statistical mechanics; partition functions for various ensembles and their connection to thermodynamics; fluctuations; noninteracting quantum and classical gases; heat capacity of solids; adsorption; phase transitions and order parameters; linear response theory; structure of classical fluids; computer simulation methods.
Instructor: Wang

Chemical Thermodynamics

9 units (3-0-6)  |  first term
An advanced course emphasizing the conceptual structure of modern thermodynamics and its applications. Review of the laws of thermodynamics; thermodynamic potentials and Legendre transform; equilibrium and stability conditions; metastability and phase separation kinetics; thermodynamics of single-component fluid and binary mixtures; models for solutions; phase and chemical equilibria; surface and interface thermodynamics; electrolytes and polymeric liquids.
Instructor: Wang

Biochemistry and Biophysics of Macromolecules and Molecular Assemblies

9 units (3-0-6)  |  first term
Detailed analysis of the structures of the four classes of biological molecules and the forces that shape them. Introduction to molecular biological and visualization techniques. Not offered in 2019-20.

Atmospheric Chemistry I

9 units (3-0-6)  |  third term
A detailed course about chemical transformation in Earth's atmosphere. Kinetics, spectroscopy, and thermodynamics of gas-phase chemistry of the stratosphere and troposphere; sources, sinks, and lifetimes of trace atmospheric species; stratospheric ozone chemistry; oxidation mechanisms in the troposphere. Offered 2019-20.
Instructors: Seinfeld, Wennberg

Atmospheric Chemistry II

3 units (3-0-0)  |  first term
A lecture and discussion course about active research in atmospheric chemistry. Potential topics include halogen chemistry of the stratosphere and troposphere; aerosol formation in remote environments; coupling of dynamics and photochemistry; development and use of modern remote-sensing and in situ instrumentation. Graded pass/fail. Not offered 2019-20.
Instructors: Seinfeld, Wennberg

Biophysical/Structural Methods

9 units (3-0-6)  |  second term
Basic principles of modern biophysical and structural methods used to interrogate macromolecules from the atomic to cellular levels, including light and electron microscopy, X-ray crystallography, NMR spectroscopy, single molecule techniques, circular dichroism, surface plasmon resonance, mass spectrometry, and molecular dynamics and systems biological simulations.
Instructors: Clemons, Jensen, and other guest lectures

Advanced Topics in Biochemistry and Biophysics

6 units (3-0-3)  |  first term
Discussion of research fields in biochemistry and molecular biophysics at Caltech.
Instructors: Clemons, Hoelz, Shan and various guest lecturers

Physical Chemistry of Engineered Waters

9 units (3-0-6)  |  second term
This course will cover selected aspects of the chemistry of engineered water systems and related water treatment processes. Lectures cover basic principles of physical-organic and physical-inorganic chemistry relevant to the aquatic environment under realistic conditions. Specific topics include acid-base chemistry, metal-ligand chemistry, redox reactions, photochemical transformations, biochemical transformations, heterogeneous surface reactions, catalysis, and gas-transfer dynamics. The primary emphasis during the winter term course will be on the physical chemistry of engineered waters.
Instructor: Hoffmann

Physical Organic Chemistry of Natural Waters

9 units (3-0-6)  |  third term
This course will cover selected aspects of the chemistry of natural and engineered aquatic systems. Lectures cover basic principles of physical-organic and physical-inorganic chemistry relevant to the aquatic environment under realistic conditions. Specific topics that are covered include the principles of equilibrium chemistry in natural water, acid-base chemistry of inorganic and organic acids including aquated carbon dioxide, metal-ligand chemistry, ligand substitution kinetics, kinetics and mechanisms of organic and inorganic redox reactions, photochemical transformations of chemical compounds, biochemical transformations of chemical compounds in water and sediments, heterogeneous surface reactions and catalysis. Thermodynamic, transport, kinetics and reaction mechanisms are emphasized. The primary emphasis during the spring term course will be on the organic chemistry of natural waters emphasizing the fate and behavior of organic compounds and persistent organic pollutants in the global environment.
Instructor: Hoffmann

Macromolecular Function: Kinetics, Energetics, and Mechanisms

9 units (3-0-6)  |  second term
Discussion of the energetic principles and molecular mechanisms that underlie enzyme's catalytic proficiency and exquisite specificity. Principles of allosteric regulation, selectivity, and enzyme evolution. Practical kinetics sections discuss how to infer molecular mechanisms from rate/equilibrium measurements and their application to more complex biological systems, including steady-state and pre-steadystate kinetics, kinetic simulations, and kinetics at the single molecule resolution.
Instructor: Shan

Chemical Research

Units by arrangement  | 
Offered to M.S. candidates in chemistry. Graded pass/fail.
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