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Thursday, December 05, 2019
4:00 PM - 5:00 PM
Spalding Laboratory 106 (Hartley Memorial Seminar Room)

Chemical Engineering Seminar

Designing Biology
Reshma Shetty, Co-founder, Gingko Bioworks,
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Biology is the most powerful technology on the planet. It’s ability to self repair, self replicate and make atomically precise structures is unparalleled among manufacturing technologies. At Ginkgo, we are passionate about harnessing the power of biology by designing it. Unfortunately, despite significant advancements in recent years, the tools and technology for biological design remain woefully inadequate relative to the potential of biological technology. Our limited understanding of how biology works means that, for now, biological design is essentially a search problem. At Ginkgo, we are leveraging automation and software to build a genetic engineering foundry that allows us to more cheaply and scalably search potential biological design space for functional organism designs. In particular, I will highlight the value of combining computer-aided engineering software tools, cheap gene synthesis and high resolution-accurate mass LCMS to develop engineered microbes. Then, I'll discuss how we applied these technologies for improving a "living medicine" for the treatment of a metabolic disorder.

For more information, please contact Sohee Lee by phone at 6263954193 or by email at sohee@caltech.edu.