From Nature to the Pharmacy: The Chemistry Behind Modern Medicines

Natural products—molecules originally isolated from bacteria, fungi, plants, and other sources—often have medicinal values that can be enhanced by careful reengineering.

Research for a Greener Future

Today's Earth Week feature highlights three cross-disciplinary research centers where Caltech scientists and engineers collaborate on projects that will have a positive impact on energy, the environment, and Earth's sustainable future.

Watching the Brain Do Its Thing: An Interview with Mikhail Shapiro

To a large extent, the brain remains a black box. Taking it out of its case inside the skull and examining it—as in an autopsy—reveals some things, but not how the brain works in a living, functioning being. Assistant Professor of Chemical Engineering Mikhail Shapiro is determined to reveal the mysteries of the brain in situ, in living beings, right down to the cellular level.

New Method Could Improve Ultrasound Imaging

One day while casually reading a review article, Caltech chemical engineer Mikhail Shapiro came across a mention of gas vesicles—tiny gas-filled structures used by some photosynthetic microorganisms to control buoyancy. It was a light-bulb moment. Shapiro is always on the lookout for new ways to enhance imaging techniques such as ultrasound or MRI, and the natural nanostructures seemed to be just the ticket to improve ultrasound imaging agents.

Caltech Appoints Diana Jergovic to Newly Created Position of Vice President for Strategy Implementation

In the newly created position, Jergovic will collaborate closely with the president and provost, and with the division chairs, faculty, and senior leadership on campus and at the Jet Propulsion Laboratory.

Resourceful Computing Advances Chemistry at Caltech

In the 1970s, Caltech researcher Aron Kuppermann found additional computer resources in an unlikely place: a local religious organization. In the same spirit of creativity, Caltech researchers today have also found ways to practice resourceful computing.

National Inventors Hall of Fame to Induct Frances Arnold

Frances H. Arnold, the Dick and Barbara Dickinson Professor of Chemical Engineering, Bioengineering and Biochemistry, and director of the Donna and Benjamin M. Rosen Bioengineering Center at Caltech, is one of five living innovators chosen to be inducted into the National Inventors Hall of Fame in 2014.

A Changing View of Bone Marrow Cells

Using a novel microfluidic technique, researchers at Caltech have shown that blood stem cells might be more actively involved in battles against infection. Rather than simply replenishing immune cells after they become depleted, new research shows that blood stem cells sense danger signals directly and quickly produce new immune cells.

Watching the Brain Do Its Thing: An Interview with Mikhail Shapiro

To a large extent, the brain remains a black box. Taking it out of its case inside the skull and examining it—as in an autopsy—reveals some things, but not how the brain works in a living, functioning being. Assistant Professor of Chemical Engineering Mikhail Shapiro is determined to reveal the mysteries of the brain in situ, in living beings, right down to the cellular level.

Theodor Agapie Wins Presidential Early Career Award

Theodor Agapie, assistant professor of chemistry at the California Institute of Technology (Caltech), is a 2014 recipient of a Presidential Early Career Award for Scientists and Engineers (PECASE). Agapie will receive the award from President Barack Obama at a ceremony in the nation's capital later this year.

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