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Undergraduate, Graduate, Post-Doc Opportunities

Catapower Inc.

Catapower Inc., a cleantech startup company based in southern California, is seeking interest in 3 positions in our technical team.

Director of Chemistry

Anticipated role and responsibilities: The director of chemistry will work with company leadership to manage optimization, scaleup, and product isolation from our proprietary glycerol-to-lactate process. This will include lab design and setup, technical planning, development of laboratory procedures, safety oversight, and some portions of the company's business development activities. He or she will work closely with the company's technical founders and manage our technical staff. Qualifications: The successful candidate will have experience in synthetic chemistry, including process development. A Ph.D. in synthetic chemistry or chemical engineering is preferred. Masters-level candidates will also be considered with appropriate industrial experience.

Laboratory Technicians (2)

Anticipated role and responsibilities: Our technicians will work with the founders and the director of chemistry to optimize chemical process and manufacture qualification samples of products. This work will include synthetic and analytical chemistry work as well as some administrative functions of the company related to manufacturing. Qualifications: Successful candidates will have a BS or MS degree in chemistry or chemical engineering with training in synthetic chemistry.

Technology

Our core technology originated at the University of Southern California and is summarized in these papers: DOI 10.1021/acscatal.5b02732, 10.1021/acssuschemeng.8b00653, 10.1038/ncomms11308.

Compensation and Timeline

Catapower is a technology startup and will compensate employees with a combination of salary and equity, commensurate with experience. Initial contracts will be made for one year, with the intent to renew as funding is secured. We anticipate making hires in summer 2020.

Point of Contact

For information on this position, please contact Travis Williams, co-founder travisw@catapowerinc.com

Download the job posting here.


James Boswell Postdoctoral Fellowship

The California Institute of Technology and The Huntington Medical Research Institutes announce the availability of an endowed postdoctoral fellowship for collaborative research. This one-year fellowship, renewable for a second year, is open to individuals who recently received their doctorate and are interested in doing research in the areas of interest to researchers at Caltech and HMRI. These areas include, but are not limited to, magnetic resonance imaging and spectroscopy, molecular neuroscience, and medicinal chemistry.

The fellow will have an appointment at Caltech and will work with a member of the professorial faculty at Caltech. The fellow will have an appointment and an office at HMRI and work with several mentors including Kevin King, MD, Director of Imaging Research; Alfred N. Fonteh, PhD, Lipid Biochemistry; Xianghong Arakaki, MD, PhD, Electrophysiology; Michael Harrington, MD (MB, ChB) FRCP, Director of Neurosciences, depending on project chosen.

This one-year appointment, renewable for a second year, provides an annual salary of $58,240 to $60,000, commensurate with the fellow's qualifications and experience. Start date is negotiable but ideally September 1, 2020.

The fellowship is open to postdoctoral scholars with a PhD in their relevant field.

Applications should include

- curriculum vitae,

- two-page statement of research interests and accomplishments,

- proposed mentors at both Caltech and HMRI (please indicate if you have discussed it with the mentor),

- one representative manuscript (published or submitted),

- 2-3 letters of reference

Application should be submitted to: aliciac@caltech.edu

Application closing date: July 31, 2020

Caltech is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to age, race, color, religion, sex, sexual orientation, gender identity, or national origin, disability status, protected veteran status, or any other characteristic protected by law.


Codiak

Scientist II, Downstream Process Development

Codiak is driven by a belief that the most innovative medicines are found at the intersections of scientific fields and that problem-solving across disciplinary boundaries is necessary to be a leader in bionanoparticle therapeutics. The Downstream Processing group at Codiak is seeking a talented, creative, and passionate candidate motivated to bring impactful therapeutic modalities to patients with unmet medical needs. The group prides itself on integrity and collaboration while almost always finding time to have fun at work.

The Scientist will develop and optimize the company's novel exogenous exosome/synthetic nucleic acid loading platform. The successful candidate will be highly motivated, thrive on increasing levels of responsibility, and have a demonstrated capability to drive science in a fast-paced environment. Responsibilities will include providing technical/scientific expertise and leadership in all areas of drug process development such as loading, cleanup, filtration, and formulation. Additional responsibilities will include assisting in the development of processes for the purification of exosomes.  

Essential Functions/Responsibilities

  1. Design, execute, and analyze pioneering loading processes for diverse molecules, including ASOs, siRNA, mRNA, and small molecules.
  2. Develop unit operations to enable cleanup and formulation of durably loaded drug product.
  3. Scale-up processes from bench to pilot and cGMP clinical manufacturing scale, including technology transfer through clinical manufacturing.
  4. Create state-of-the-art small-scale models and characterization capabilities.
  5. Identify, engage, and manage external collaborators to explore new loading technologies
  6. Assist in the development and execution of purification processes as needed.
  7. Seek to connect structural attributes and functional potency of loaded drug product.
  8. Perform document writing, data interpretation, presentation, statistical analysis, and trending.
  9. Serve as function lead on pipeline programs to guide them to successful completion, requiring cross-functional collaboration and scientific and technical expertise. 
  10. Author scientific manuscripts and patents. Present work internally and externally.
  11. Aid in the authoring of Regulatory documents. 

Requirements

Ph.D. in chemistry, polymer chemistry, biochemical engineering or similar disciplines with a minimum of 2 years related experience; expert knowledge of scientific principles and concepts;

A. Proficient in organic, polymer, and bioconjugation chemistry;

B. Experience developing processes with exosomes, liposomes, and/or lipid nanoparticles;

C. Background in applying advanced technologies to develop methods for loading of payloads into and onto nanoparticles;

D. Experience in development and transfer of production processes for nanoparticles to cGMP manufacturing organizations;  

E. Demonstrated technical proficiency, work ethic, scientific creativity, collaboration with others and independent thought;

F. Excellent communication and presentation skills (oral and written);

G. Reputation as emerging leader in field with sustained performance and accomplishment

Click here to apply