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David A. Tirrell
Ross McCollum-William H. Corcoran Professor and Professor of Chemistry and Chemical Engineering

Proc. Natl. Acad. Sci. USA (Epub Aug. 17, 2009). I. C. Tanrikulu, E. Schmitt, Y. Mechulam, W. A. Goddard III and D. A. Tirrell. "Discovery of E. coli methionyl-tRNA synthetase mutants for efficient labeling of proteins with azidonorleucine in vivo."

Nature Chemical Biology (Epub Aug. 9, 2009). J. T. Ngo, J. A. Champion, A. Mahdavi, I. C. Tanrikulu, K. E. Beatty, R. E. Conner, T. H. Yoo, D. C. Dieterich, E. M. Schuman and D. A. Tirrell. "Cell-Selective Metabolic Labeling of Proteins."

Physical Biology: From Atoms to Medicine, A. H. Zewail, ed., Imperial College Press, London (2008), p. 165-187, D. A. Tirrell. "Reinterpreting the Genetic Code: Implications for Macromolecular Design, Evolution and Analysis."

Macromolecules, 41, 1839 (2008). P. J. Nowatzki, C. Franck, S. A. Maskarinec, G. Ravichandran and D. A. Tirrell. "Mechanically Tunable Thin Films of Photosensitive Artificial Proteins: Preparation and Characterization by Nanoindentation."

ChemBioChem, 9, 366 (2008). R. E. Connor, K. Piatkov, A. Varshavsky and D. A. Tirrell. "Enzymatic N-terminal Addition of Non-Canonical Amino Acids to Peptides and Proteins."

J. Am. Chem. Soc., 129, 4874 (2007). I. S. Carrico, S. A. Maskarinec, S.C. Heilshorn, M. Mock, J. C. Liu, P. J. Nowatzki, C. Franck, G. Ravichandran and D.A. Tirrell. "Lithographic Patterning of Photoreactive Cell-Adhesive Proteins."

Proc. Natl. Acad. Sci. USA, 104,13887 (2007). T. H. Yoo, A. J. Link and D. A. Tirrell. "Evolution of a Fluorinated Green Fluorescent Protein."

Angew. Chem. Int. Ed., 45, 7364 (2006). K. E. Beatty, J. C. Liu, F. Xie, D.C. Dieterich, E. M. Schuman, Q. Wang and D.A. Tirrell. "Fluorescence Visualization of Newly Synthesized Proteins in Mammalian Cells."Science, 273, 933 (1996). E. Evans, H. K. Bowman, A. Leung, D. Needham and D.A. Tirrell. "Biomembrane Templates for Nanoscale Conduits and Networks."

Proc. Natl. Acad. Sci. USA, 103, 9482 (2006). D.C. Dieterich, A.J. Link, J. Graumann, D.A. Tirrell and E.M. Schuman. "Selective identification of newly synthesized proteins in mammalian cells using bioorthogonal noncanonical amino acid tagging (BONCAT)."

Nature, 428, 487 (2004). R. Langer and D.A. Tirrell. "Designing Materials for Biology and Medicine. "
J. Am. Chem. Soc., 125, 11164 (2003). A.J. Link and D.A. Tirrell. "Cell Surface Labeling of Escherichia Coli via Copper (l)-Catalyzed [3+2] Cycloaddition."

Proc. Natl. Acad. Sci. USA, 99, 19 (2002). K.L. Kiick, E. Saxon, C.R. Bertozzi and D.A. Tirrell. "Incorporation of Azides into Recombinant Proteins for Chemoselective Modification by the Staudinger Ligation."__
J. Am. Chem. Soc., 122, 1282 (2000). J.C.M. van Hest, K.L. Kiick and D.A. Tirrell. "Efficient Incorporation of Unsaturated Methionine Analogues into Proteins in vivo."

Science, 281, 389 (1998). W. A. Petka, J. L. Harden, K. P. McGrath, D. Wirtz and D.A. Tirrell. "Reversible Hydrogels from Self-Assembling Artificial Proteins."

Nature, 389, 167 (1997). S.M. Yu, V. Conticello, G.H. Zhang, C. Kayser, M.J. Fournier, T.L. Mason and D.A. Tirrell. "Smectic Ordering in Solutions and Films of a Rod-like Polymer Owing to Monodispersity of Chain Length."

Science, 265, 1427 (1994). M.T. Krejchi, E.D.T. Atkins, A.J. Waddon, M.J. Fournier, T.L. Mason and D.A. Tirrell. "Chemical Sequence Control of ß-Sheet Assembly in Macromolecular Crystals of Periodic Polypeptides."